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Karuna Garg [M.D.]

  • Titles : Professor Department of Pathology
  • Affiliations : Cleveland Clinic

  1. Garg K, Soslow RA, Rivera M, Tuttle MR and Ghossein RA.  Histologically bland extremely well differentiated thyroid type carcinomas arising in struma ovarii can recur and metastasize.  Int J Gynecol Pathol 2009;28(3):222-230.2009
  2. Garg K, Leitao MM, Kauff ND, Hansen J, Kosarin K, Shia J and Soslow RA.  Selection of endometrial carcinomas for DNA mismatch repair protein immunohistochemistry using patient age and tumor morphology enhances detection of mismatch repair abnormalities. Am J Surg Pathol 2009; 33:925-933.
  3. Garg K, Shih K, Barakat R, Zhou Q, Iasonos A and Soslow RA. Endometrial carcinomas in women age 40 years and younger: tumors associated with loss of DNA mismatch repair proteins comprise a distinct clinicopathologic subset.  Am J Surg Pathol 2009; 33(12): 1869-1877.
  4. Garg K, Leitao M, Wynveen C, Sica GL, Shia J, Shi W and Soslow RA.  p53 overexpression in morphologically ambiguous endometrial carcinomas correlates with adverse clinical outcomes.  Mod Pathol 2010; 23(1): 80-92.
  5. Tafe L, Garg K (co-first authors), Tornos C and Soslow RA.  Undifferentiated carcinomas of the uterus and ovary.  Mod Pathol 2010;23(6):781-789.
  6. Corben AD, Nehhozina T, Garg K, Vallejo CE, Brogi E. Endosalpingiosis in axillary lymph nodes: a possible pitfall in the staging of patients with breast carcinoma. Am J Surg Pathol.
  7. Garg K, Tickoo SK, Soslow RA, Reuter VE.  Morphologic features of uterine leiomyomas associated with hereditary leiomyomatosis and renal cell carcinoma syndrome: a case report.  Am J Surg Pathol 2011;35(8):1235-1237.
  8. Garg K, Broaddus RR, Soslow RA, Urbauer DL, Levine DA, Djordjevic B. Pathologic scoring of PTEN immunohistochemistry in endometrial carcinoma is highly reproducible.  Int J Gynecol Pathol 2012;31(1):48-56.
  9. Garg K, Levine DA, Olvera N, Dao F, Bisogna M, Secord AA, Berchuck A, Cerami E, Schultz N, Solsow RA.  BRCA1 immunohistochemistry in a molecularly characterized cohort of ovarian high-grade serous carcinomas.  Am J Surg Pathol 2013;37(1):138-146.
  10. Karamurzin Y, Soslow RA, Garg K.  Histologic evaluation of prophylactic hysterectomy and oophorectomy in Lynch syndrome.  Am J Surg Pathol 2013;37(4):579-585.
  11. Cancer Genomic Atlas Research Network. Integrated genomic characterization of endometrial carcinoma. Nature 2013;497(7447):67-73.
  12. Joseph NM, Solomon DA, Frizzell N, Rabban J, Zaloudek C and Garg K.   Morphology and immunohistochemistry for 2SC and FH aid in detection of fumarate hydratase gene aberrations in uterine leiomyomas from young patients. Am J Surg Pathol 2015 Nov;39(11):1529-39.
  13. Buelow B, Cohen J, Nagymanyoki Z, Frizzell N, Joseph NM, McCalmont T, Garg K. Immunohistochemistry for 2-Succinocysteine (2SC) and Fumarate Hydratase (FH) in Cutaneous Leiomyomas May Aid in Identification of Patients With HLRCC (Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome). Am J Surg Pathol. 2016 Jul;40(7):982-8.
  14. Nolan A, Joseph NM, Sangoi AR, Rabban J, Zaloudek C, Garg K. FOXL2 Mutation Status in Granulosa Theca Cell Tumors of the Ovary. Int J Gynecol Pathol. 2017;36(6):568-574.
  15. Bean GR, Anderson J, Sangoi AR, Krings G, Garg K. DICER1 mutations are frequent in müllerian adenosarcomas and are independent of rhabdomyosarcomatous differentiation. Mod Pathol 2019;32(2):280-289.
  16. Rabban JT, Chan E, Mak J, Zaloudek C, Garg K. Prospective Detection of Germline Mutation of Fumarate Hydratase in Women With Uterine Smooth Muscle Tumors Using Pathology-based Screening to Trigger Genetic Counseling for Hereditary Leiomyomatosis Renal Cell Carcinoma Syndrome: A 5-Year Single Institutional Experience. Am J Surg Pathol 2019 43(5):639-655.
  17. Chan E, Rabban JT, Mak J, Zaloudek C, Garg K. Detailed Morphologic and Immunohistochemical Characterization of Myomectomy and Hysterectomy Specimens From Women With Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome (HLRCC). Am J Surg Pathol. 2019;43(9):1170-1179. 
  18. Ladwig NR, Umetsu SE, Zaloudek C, Rabban J, Garg K. Corded and Hyalinized Endometrioid Adenocarcinoma (CHEC) of the Uterine Corpus are Characterized by CTNNB1 Mutations and Can Show Adverse Clinical Outcomes. Int J Gynecol Pathol 2020 Sep 8. doi: 10.1097/PGP.0000000000000671. Online ahead of print.
  19. Joehlin-Price A, Van Ziffle J, Hills NK, Ladwig N, Rabban JT, Garg K. Molecularly Classified Uterine FIGO Grade 3 Endometrioid Carcinomas Show Distinctive Clinical Outcomes But Overlapping Morphologic Features. Am J Surg Pathol 2020 Oct 5. doi: 10.1097/PAS.0000000000001598. Online ahead of print.

  • New Developments in the Pathology of Women's Cancers: What Every Pathologist Needs to Know
  • Surgical Pathology of the GI, GYN and GU Tracts and Tumors of Soft Tissue and Endocrine Organs: Practical Tips for the Practicing Pathologist

Past Lectures

  • Endocervical Adenocarcinoma: The New WHO Paradigm for Classification, Staging and Stromal Invasion Pattern (10/13/2022)
  • Uterine Mesenchymal Tumors: The Old and the New (10/12/2022)
  • Gynecologic Pathology Virtual Interactive Slide Seminar 1: Endometrial Biopsy Pitfalls and Important Managerial Implications (10/11/2022)
  • Endometrial Carcinomas: Diagnostic Issues in Classification and Staging (10/11/2022)
  • Ovarian Non-Serous Epithelial Tumors: Practical Solutions for Classification, Reporting and Staging (10/10/2022)
  • Ovarian Epithelial Tumors (06/25/2021)
  • Uterine Mesenchymal Neoplasms: An Approach to Common Diagnostic Challenges (06/24/2021)
  • Endometrial Carcinoma: Classification in the Molecular Era (06/23/2021)
  • Slide Seminar: Endometrial Biopsy Interpretation: A Practical Approach (06/22/2021)
  • Endocervical Adenocarcinoma: Recent Updates (06/21/2021)


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